Therapeutic options to treat mustard gas poisoning – Review

Therapeutic options to treat sulfur mustard poisoning--the road ahead.

For the past 15 years the international research community has conducted a basic and applied research program aimed at identifying a medical countermeasure against chemical threat vesicant, or blistering, agents. The primary emphasis of this program has been the development of therapeutic protection against sulfur mustard and its cutaneous pathology-blister formation. In addition to the work on...

Poisoning by "Mustard" Gas

Preventive measures against the mustard gas: a review

  The main aim in this study was to collect the experiences of Iranian researchers about sulfur mustard (SM) and provide a guideline for the prevention of abuse for this dangerous agent. We searched valid national and international databases using related key words in the two languages. We found 193 articles which had been published in medical journals. Among them, 25 articles had some implicat...

Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis?

Leishmaniasis is a neglected disease, which needs improvements in drug development, mainly due to the toxicity, parasite resistance and low compliance of patients to treatment. Therefore, the development of new chemotherapeutic compounds is an urgent need. This opinion article will briefly highlight the feasible use of calpain inhibitors as leading compounds to search for new therapeutic option...

TRANSIENT DECREASED SERUM TESTOSTERONE AFTER EXPOSURE TO MUSTARD GAS

The effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young Iranian men. In the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. Three of 13 men had total testosterone below 300 ng/dL and two of ...

Natural Therapeutic Options in Endodontics - A Review

Complete eradication of microbial biofilms and elimination of the smear layer are the key factors during endodontic treatment. Various chemical irrigants have been proposed in the literature for the same. The major setback with these chemical irrigants is that they are not bio-friendly to the dental and peri-radicular tissues. In the recent years, research to use natural products for root canal...